St. James Seminary is a senior high school in Sunyani, the capital of the Bono region of Ghana, founded in 1978 by Most Rev. James Kwadwo Owusu, the late bishop of the Roman Catholic Diocese of Sunyani. It is not just a Senior High School, but also a Catholic Minor Seminary which offers a wide range of opportunities for both seminarians and non-Seminarians to make them not only aware of their potentials, but to fulfill them. The school emphasizes moral, spiritual and positive character formation in addition to striving to achieve academic excellence. St. James has been adjudged the best senior high school in Ghana over the past decade having featured consecutively in the list of top ten performing schools in the West African Examinations Council’s Senior School Certificate Exams (WASSCE) over the period. It topped the WASSCE in 2006, 2009 and 2011 and produced the overall best and third best candidates in West Africa in the 2016 exam.
Students of St. James are nicknamed ‘The Saints’ to tout their high moral uprightness and spirituality akin to the characteristics of saints. An alumnus of St. James Seminary Senior High School is openly called “Ɔhotenii” (pl. Ahotefoɔ), the Twi word for a saint.